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Halobetasol Topical

Generic name: halobetasol topical [ HAL-oh-BAY-ta-sol ]
Brand names: Bryhali, Lexette, Ultravate, Ultravate X Ointment, Ultravate X Cream
Dosage forms: topical cream (0.05%), topical foam (0.05%), topical lotion (0.01%; 0.05%), topical ointment (0.05%)
Drug class: Topical steroids

Medically reviewed by Carmen Pope, BPharm. Last updated on Jun 13, 2023.

What is halobetasol topical?

Halobetasol topical is a super high potency, Class I corticosteroid product that is applied to the skin to reduce inflammation and itching caused by plaque psoriasis or other skin conditions that respond to corticosteroid medication.

Halobetasol topical is available as a cream, ointment, lotion, or foam:

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Halobetasol (halobetasol propionate) is a highly potent, Class I corticosteroid that can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing’s syndrome, hyperglycemia, and glucosuria. Do not use for longer than 2 weeks and do not exceed the recommended dose. Periodic monitoring for HPA suppression may be required.

Before taking this medicine

You should not use halobetasol topical if you are allergic to it.

Halobetasol topical should not be applied to lesions that are exuding serum or to skin folds (where two areas of skin touch each other).

Tell your doctor if you have ever had:

Topical corticosteroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Children are more susceptible to systemic absorption of topical corticosteroids. Most preparations of halobetasol topical are not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

It is not known whether halobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. If you are instructed to use halobetasol topical, use a small amount for the shortest time possible.

It may not be safe to breastfeed while using this medicine. If you are instructed to use halobetasol topical, use a small amount for the shortest time possible. Do not apply to the breasts.

How do I use halobetasol topical?

Use halobetasol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take it by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or sunburned, windburned, dry, or irritated skin. Rinse with water if halobetasol gets in your eyes or mouth.

Wash your hands before and after using halobetasol, unless you are using this medicine to treat the skin on your hands.

Shake the foam before each use.

Call your doctor if your symptoms do not improve after 2 weeks (8 weeks for psoriasis), or if they get worse. Stop using the product if your symptoms improve sooner.

What happens if I miss a dose?

Apply the product as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of halobetasol topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using halobetasol topical?

What are the side effects of halobetasol topical?

Get emergency medical help if you have signs of an allergic reaction to halobetasol, such as hives; difficulty breathing; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Common halobetasol side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect halobetasol topical?

Halobetasol topical is unlikely to interact with other medications you may take. But you should not use it with other topical or oral corticosteroids, because they may have an additive effect.

Tell your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Storage

Store at room temperature away from moisture and heat. Do not freeze.

Keep halobetasol topical foam away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty canister.

Popular FAQ

Halobetasol and clobetasol are both classified as super high-potency or high-potency topical corticosteroid (“steroid”) creams used on the skin. They are both FDA-approved to treat plaque psoriasis and skin conditions that are responsive to topical corticosteroids, such as dermatitis and eczema (atopic dermatitis). They lessen skin redness and pain, itching, dryness and scaling. Continue reading

Which topical corticosteroid (“steroid”) product is best for you depends upon what skin condition you have, your symptoms and where it is located on your body. Other selection factors may include availability, cost and if the medicine is covered by your insurance. After examination, your doctor will be able to determine which topical steroid is best to treat your skin condition. Continue reading

No, halobetasol propionate is not available as an over-the-counter (OTC) product. Topical halobetasol is a highly potent prescription medicine used on the skin that reduces inflammation in psoriasis, eczema, dermatitis and other corticosteroid-responsive conditions. Continue reading

Halobetasol should not be used on the scalp, face, groin or armpit, although it is used on the skin in other areas of the body. Continue reading

Halobetasol can be applied to the skin to treat the redness, itching and swelling caused by poison ivy in patients 12 years of age and older. It is considered a super-high potency topical anti-inflammatory corticosteroid. It requires a prescription and comes as a cream, ointment, foam, or lotion. Generic and brand name products are available. Continue reading

Halobetasol should not be used on the face or for acne because it is a super-high potency topical corticosteroid. The skin on the face is quite thin compared with the skin on other areas of the body and using halobetasol on the face can increase the risk of acne and other side effects such as dryness, irritation, itching, redness, red or purple blotches underneath the skin, skin discoloration or thinning, small red or white bumps or a rash around the mouth, or unwanted hair growth. Continue reading

There is no limit on how long you can use Duobrii Lotion, but you should stop using it when your psoriasis has cleared and your doctor tells you to stop treatment. Once your skin is clear it may stay that way for up to 3 months after treatment. Continue reading

Even though Duobrii is a medicine used on the skin, it is highly potent. Excessive doses can pass through your skin and into your bloodstream, which may lead to serious side effects like suppression of your natural cortisol production, Cushing syndrome, high blood sugar or vision problems. Follow your doctor’s dosing instructions exactly. Continue reading

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.